New York, NY – The Clinton Foundation marks 25 years since President Clinton opened the Foundation’s doors in Harlem. In the two and a half decades since opening, the Foundation has built a pathbreaking record of impact around the world:

• More than 500 million people reached across 180 countries through Clinton Global Initiative (CGI) programs and partnerships;
• 30 million patients reached with lifesaving medications through the Clinton Health Access Initiative;
• 31 million children supported through the Alliance for a Healthier Generation;
• 1 million cumulative doses of naloxone distributed through the Overdose Response Network; and
• 525,000 students engaged through the Clinton Presidential Center.

The Foundation’s work in Harlem over the years includes the Clinton Economic Opportunity Initiative that helped small businesses in the neighborhood expand; CGI Commitments to Action that gave residents better access to microfinance and food assistance, and distributing thousands of books and improving nutrition and physical activity in Harlem schools through Too Small to Fail and the Alliance for a Healthier Generation. 

Earlier this year, Inside Philanthropy published “Bill Clinton’s Philanthropic Legacy: An Appraisal,” concluding:

“Through the Clinton Foundation, the Clinton Global Initiative (CGI) and other activities — including donating millions of dollars of his own money — Clinton has compiled a record of philanthropic impact since leaving office in 2000 that is unmatched by any former president and far more extensive than most people realize.”

“At the center of that impressive record is the Clinton Health Access Initiative (CHAI), which has helped millions of people gain access to antiretroviral drugs, especially in sub-Saharan Africa, since its founding in 2002. This work has likely saved hundreds of thousands of lives…” 

“Clinton’s philanthropic footprint has extended well beyond global health, reflecting his famously broad interests and deep curiosity. Both on his own and with both former Bush presidents, Clinton has helped raise hundreds of millions of dollars for humanitarian disasters — most notably, the devastating 2004 tsunami in Asia, Hurricane Katrina and the 2010 earthquake in Haiti. His foundation and CGI have also worked on climate change, domestic poverty, education, gender equity, and more.”

The piece also cites the Clinton Global Initiative as a “groundbreaking model for social impact”: “Nothing like CGI existed before its creation in 2005, and it’s hard to think of anything quite like it that’s emerged since then … it remains one of the more innovative and potent philanthropic efforts of our time.”

Read more at Inside Philanthropy.

In 2026 and beyond, this work is continuing and expanding:

• This September, President Clinton, Secretary Clinton, and Dr. Chelsea Clinton will host global leaders from around the world at the Clinton Global Initiative 2026 Annual Meeting, advancing commitments that are tackling our most urgent crises. Learn more.
• This month, the Foundation launched the Clinton Policy Institute – the first new initiative in more than a decade, dedicated to improving the lives of children and families by developing, accelerating, and scaling common-sense policy solutions, especially at the state and local levels. Learn more.
• The Clinton Health Access Initiative is part of a landmark partnership making the revolutionary HIV prevention tool lenacapavir available at a cost of $40 a year in 120 countries starting in 2027, more than a decade ahead of schedule. Learn more.
• The Alliance for a Healthier Generation continues to work with thousands of schools to strengthen healthy school environments, bridge school and public health systems, and advance solutions that improve health outcomes for young people across the country. Learn more.
• The Clinton Presidential Center engages people across generations and ideologies through nonpartisan leadership programs, educational and cultural experiences, and forums for courageous and collaborative conversations; since opening in 2004, it has welcomed more than 5.4 million visitors and contributed significantly to the local economy, which has expanded by $4.9 billion. 

The Foundation’s various programs are continuing their life-changing work, including Too Small to Fail reaching parents and caregivers with critical early childhood development skills and tools, and the Overdose Response Network expanding access to lifesaving naloxone.